A case of pancreatic mucinous cystic neoplasm accompanied by infiltrating anaplastic giant-cell carcinoma and literature review
نویسندگان
چکیده
This case was an old woman who had been suffering from peripancreatic space occupying lesions for more than 3 years. She underwent distal pancreatectomy and splenectomy. Under a microscopic examination, the tumor was composed of well-differentiated mucinous cystic neoplasm (MCN) and poorly differentiated anaplastic giant-cell carcinoma. Tumor giant-cells engulfing the neutrophils were visible in the region of anaplastic carcinoma. In terms of the immunophenotype of the neoplastic cell, CK, CK7, CA19.9 and Muc-1 were all positive; vimentin was partially positive, while CD20, CD3 and CD30 were all negative. The patient did not experience a recurrence at a 4-month follow-up. Pancreatic mucinous cystic neoplasm accompanied by infiltrating anaplastic giant-cell carcinoma is rarely reported. It belongs to a rare malignant pancreatic epithelial neoplasm, wherein the MCN maybe the limbo of anaplastic carcinoma, which ultimately transforms into anaplastic carcinoma.
منابع مشابه
Anaplastic carcinoma of the pancreas associated with a mucinous cystic adenocarcinoma. A case report and review of the literature.
CONTEXT Anaplastic carcinoma of the pancreas is a rare undifferentiated variant of ductal adenocarcinoma, which commonly displays sarcomatoid spindle-cell and pleomorphic growth patterns. Anaplastic carcinoma of the pancreas associated with mucinous cystic neoplasm has rarely been reported. CASE REPORT Here we report a unique case of an anaplastic carcinoma of the pancreas in association with...
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